Multiple sclerosis: Time is brain

Time is brain is a call to action that is increasingly recognised and being heeded in the treatment of people with MS. By achieving the 100 day goal for diagnosis, treatment initiation, and support service provision, relapses and disability progression could be positively impacted, which in turn may reduce the long-term resource burden for many patients.

100 day challenge: Optimal timeline for brain health 1

For more information please download our leaflet


  1. Hobart J, et al. International consensus on quality standards for brain health-focused care in multiple sclerosis. MultScler. 2018: 1352458518809326.
  2. NICE clinical guideline [CG186] Multiple sclerosis in adults: management (2014). Available at:
  3. NICE quality standard [QS108] Multiple sclerosis (2016). Available at:
  4. NHS England (2018). Treatment algorithm for multiple sclerosis disease-modifying therapies. Available at:
  5. Llywodraeth Cymru Welsh Government (2014) Together for health – a neurological conditions delivery plan. Available at:
  6. Scottish General Standards for Neurological Care and Support (2019). Available at:
  7. Public Health Agency [Northern Ireland] (2011) Network -Engagement exercise summary report. Available at:
  8. Thompson AJ, et al. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. Lancet Neurol. 2018;17(2):162-173.
  9. Kobelt G, et al. Mult Scler. 2017; 23(8):1123-1136.
  10. Giovannoni G, et al (2015) Brain Health: time matters in multiple sclerosis. Available at:
  11. Kobelt G, et al Mult Scler. 2019 Apr; 25(5):740-749).
  12. Secondary care data is taken from the English Hospital Episode Statistics (HES) database produced by the Health & Social Care Information Centre (HSCIC, Copyright © 2018, re-used with the permission of the Health & Social Care Information Centre. All rights reserved.


Biogen-21905      Date of Prep: August 2019